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Synthesis and optimization of tri(propylene glycol) glycerolate diacrylate cross-linked polystyrene resin in polypeptide synthesis: role of the macromolecular support in solid phase peptide synthesis

✍ Scribed by Sasikumar, P. G.; Kumar, K. S.; Arunan, C.; Rajasekharan Pillai, V. N.

Book ID
118043878
Publisher
Royal Society of Chemistry
Year
2002
Weight
494 KB
Volume
24
Category
Article
ISSN
1472-7781

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✍ M Roice; K.S Kumar; V.N Rajasekharan Pillai 📂 Article 📅 2000 🏛 Elsevier Science 🌐 French ⚖ 227 KB

AbstractÐA 1,4-butanediol dimethacrylate cross-linked polystyrene (PS±BDODMA) support was prepared by aqueous suspension polymerization. The C-terminal amino acid incorporation, N a -Fmoc and Boc-deprotection, acylation reactions and the removal of the target peptide from the support were optimized.