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Synthesis and NMR structural studies of the adduct of trans-diamminedichloroplatinum(II) with the DNA fragment d(GpCpG)

✍ Scribed by Gibson, Dan; Lippard, Stephen J.


Book ID
126981458
Publisher
American Chemical Society
Year
1987
Tongue
English
Weight
635 KB
Volume
26
Category
Article
ISSN
0020-1669

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## Abstract The detection and fragmentation behaviour of adducts of the chemotherapeutic __cis__‐diamminedichloroplatinum(II) (cisplatin) with the dinucleosidemonophosphates d(ApG), d(GpG) and d(TpC) as model compounds for DNA adducts in an ion trap with electrospray ionization were studied. Mainly