Synthesis and neuromuscular blocking activity of 16-(2- and 3-pyridylmethylene) dehydroepiandrosterone derivatives
β Scribed by Sonal Dubey; Amit K. Sharma; D.P. Jindal; Alan Harvey; Randhir Singh; S.L. Bodhankar
- Book ID
- 116892429
- Publisher
- Elsevier Science
- Year
- 2010
- Tongue
- English
- Weight
- 406 KB
- Volume
- 75
- Category
- Article
- ISSN
- 0039-128X
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This study consists of the synthesis, separation, and stereochemical analysis of oximino ethers, followed by a preliminary pharmacological evaluation for neuromuscular blockade. Synthesis of the compounds began with the double oximation of progesterone, which yielded EE and ZE dioximes as major prod