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Synthesis and mesogenic properties of 3,6-disubstituted cyclohex-2-en-1-ones

✍ Scribed by Brettle, Roger; Dunmur, David A.; Farrand, Louise D.; Marson, Charles M.


Book ID
120985752
Publisher
Royal Society of Chemistry
Year
1996
Tongue
English
Weight
892 KB
Volume
6
Category
Article
ISSN
0959-9428

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Diastereoselective synthesis of 3,6-disu
✍ Thomas F. Anderson; Julian G. Knight; Kirill Tchabanenko πŸ“‚ Article πŸ“… 2003 πŸ› Elsevier Science 🌐 French βš– 162 KB

In a short sequence, 5-vinyloxazolidin-2-ones were converted into the 3,6-disubstituted 3,6-dihydropyridin-2-ones via Pd-catalysed carbonylation and enolate alkylation with high diastereoselectivity. Alkylation of 6-substituted N-methylpyridin-2ones gives stereoselectively the 3,6-anti diastereoisom