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Synthesis and Mechanism of Action Studies of a Series of Norindenoisoquinoline Topoisomerase I Poisons Reveal an Inhibitor with a Flipped Orientation in the Ternary DNA−Enzyme−Inhibitor Complex As Determined by X-ray Crystallographic Analysis

✍ Scribed by Ioanoviciu, Alexandra; Antony, Smitha; Pommier, Yves; Staker, Bart L.; Stewart, Lance; Cushman, Mark


Book ID
121850966
Publisher
American Chemical Society
Year
2005
Tongue
English
Weight
700 KB
Volume
48
Category
Article
ISSN
0022-2623

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