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Synthesis and Mechanism of Action of Novel Pyrimidinyl Pyrazole Derivatives Possessing Antiproliferative Activity

โœ Scribed by Hitoshi Ohki; Kenji Hirotani; Hiroyuki Naito; Satoru Ohsuki; Megumi Minami; Akio Ejima; Yukiko Koiso; Yuichi Hashimoto

Publisher
John Wiley and Sons
Year
2003
Weight
171 KB
Volume
34
Category
Article
ISSN
0931-7597

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โœฆ Synopsis

Abstract

For Abstract see ChemInform Abstract in Full Text.

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Synthesis and Insecticidal Activity of Novel Pyrazole Methanesulfonates
โœ Finkelstein, Bruce L.; Strock, Christopher J. ๐Ÿ“‚ Article ๐Ÿ“… 1997 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 214 KB ๐Ÿ‘ 2 views

A model has been used to design novel pyrazole methanesulfonates. The pyrazole carboxamide methanesulfonates demonstrated insecticidal activity with low levels of acute mammalian toxicity. The amides formed from amines with a-branching (e.g. isopropyl and sec-butyl) demonstrated the highest level of