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Synthesis and investigation of the possible insulin-like activity of 1d-4-O- and 1d-6-O-(2-amino-2-deoxy-α-d-glucopyranosyl) myo-inositol 1-phosphate and 1d-6-O-(2-amino-2-deoxy-α-d-glucopyranosyl) myo-inositol 1,2-(cyclic phosphate)

✍ Scribed by Amparo Zapata; Yolanda León; Jose M. Mato; Isabel Varela-Nieto; Soledad Penadés; Manuel Martín-Lomas


Publisher
Elsevier Science
Year
1994
Tongue
English
Weight
791 KB
Volume
264
Category
Article
ISSN
0008-6215

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✦ Synopsis


The synthesis of the glycosyl-mya-inositol l-phosphates 1 and 2 and of the glycosyl-myoinositol 1,2-(cyclic phosphate) 3, starting from previously synthesized intermediates, is reported.

Compound 3 was found to display proliferative effects on the early developing inner ear of chick embryo.


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