Synthesis and intracellular distribution of cathepsins E and D in differentiating murine friend erythroleukemia cells
β Scribed by Hideaki Sakai; Yuzo Kato; Kenji Yamamoto
- Book ID
- 115709338
- Publisher
- Elsevier Science
- Year
- 1992
- Tongue
- English
- Weight
- 885 KB
- Volume
- 294
- Category
- Article
- ISSN
- 0003-9861
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Nucleotide pool imbalances have been reported to affect the fidelity of DNA replication and repair in prokaryotic and eukaryotic cells. We have reported previously that the mutagen-hypersensitive thymidine kinase (TK)-deficient Friend erythroleukemia (FEL) cells (subclones 707BUF and 707BUE), have a
## Abstract Erythroid differentiation of Friend leukemia cells is enhanced when the cells are grown for four days in the presence of dimethylsulfoxide (DMSO). Dimethylformamide (DMF) has a similar though less marked effect. 5βBromoβ2β²βdeoxyuridine (BUdR) (10^β5^M) inhibits both DMFβ and DMSOβstimul