A model has been used to design novel pyrazole methanesulfonates. The pyrazole carboxamide methanesulfonates demonstrated insecticidal activity with low levels of acute mammalian toxicity. The amides formed from amines with a-branching (e.g. isopropyl and sec-butyl) demonstrated the highest level of
Synthesis and Insecticidal Activity of Novel Pyridine Methanesulfonates
β Scribed by Finkelstein, Bruce L.; Martz, Melissa A.; Strock, Christopher J.
- Publisher
- John Wiley and Sons
- Year
- 1997
- Tongue
- English
- Weight
- 185 KB
- Volume
- 50
- Category
- Article
- ISSN
- 1526-498X
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β¦ Synopsis
A model has been developed which has led to the design and synthesis of novel 6-methanesulfonyloxypyridine-2-carboxamides with insecticidal activity, low mammalian toxicity and safety to aquatic organisms. The amides formed from amines with a branching (e.g. isopropyl and sec-butyl) demonstrated the highest level of activity. Rice nursery box Γeld test results on laboratory raised insects gave insufficient control of the entire Japanese hopper spectrum to warrant further development of these compounds.
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