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Synthesis and Incorporation of the First Polyketide Synthase Free Intermediate in Monocerin Biosynthesis

✍ Scribed by Lorraine C. Axford; Thomas J. Simpson; Christine L. Willis


Publisher
John Wiley and Sons
Year
2004
Tongue
English
Weight
118 KB
Volume
43
Category
Article
ISSN
0044-8249

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✦ Synopsis


Monocerin (5) is a polyketide fungal metabolite that exhibits antifungal, insecticidal, and plant pathogenic properties. It has been isolated from several fungal species, including Dreschlera monoceras, [1] D. ravenelii, [2] Exserohilum turcum, [3] and, along with the related fusarentin ethers, for example, 4, from Fusarium larvarum. [4] Polyketide metabolites are pro-[


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