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Synthesis and in Vitro Hydroxyapatite Binding of Peptides Conjugated to Calcium-Binding Moieties

โœ Scribed by Murphy, Matthew B.; Hartgerink, Jeffrey D.; Goepferich, Achim; Mikos, Antonios G.

Book ID
120431988
Publisher
American Chemical Society
Year
2007
Tongue
English
Weight
178 KB
Volume
8
Category
Article
ISSN
1525-7797

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## Abstract New peptidesโ€”9โ€aminoacridine conjugates with an ethylene diamine linkerโ€”have been synthesized (both solution and solid phase methods were used) and their interactions with DNA have been studied. The affinity of Hโ€Pheโ€Glnโ€Glyโ€Ile~2~โ€NHCH~2~CH~2~NHโ€Acr conjugate and of its extended analog