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Synthesis and in vitro evaluation of novel pro-drugs for the treatment of nephropathic cystinosis

✍ Scribed by Ziad Omran; Kevin A. Moloney; Amina Benylles; Graeme Kay; Rachel M. Knott; Donald Cairns


Book ID
108073019
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
412 KB
Volume
19
Category
Article
ISSN
0968-0896

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The aim of this study was to estimate colon-specific drug delivery of a novel capsule (CS capsule). Theophylline was used as model drug and little was released from the CS capsules in the release medium mimicking physiological environment of stomach to small intestine. However, 66.7 +/- 8.8% theophy