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Synthesis and in Vitro Evaluation of Inhibitors of Intestinal Cholesterol Absorption

✍ Scribed by Werder, Moritz; Hauser, Helmut; Carreira, Erick M.

Book ID
120470361
Publisher
American Chemical Society
Year
2005
Tongue
English
Weight
445 KB
Volume
48
Category
Article
ISSN
0022-2623

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Selective lipid transport through the brush-border membrane in the small intestine of mammals is mediated by membrane-bound proteins, the so-called scavenger receptors of class B, type I or II (SR-BI or -BII). These, in turn, are inhibited by certain proteins and synthetic a-peptides that have an am