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Synthesis and in vitro antitumor activity of 1,3,4-thiadiazole derivatives based on benzisoselenazolone

โœ Scribed by Jie Zhao; Bao Quan Chen; Yan Ping Shi; Yu Ming Liu; Hai Chuan Zhao; Ji Cheng


Book ID
116350343
Publisher
Chinese Electronic Periodical Services
Year
2012
Tongue
English
Weight
174 KB
Volume
23
Category
Article
ISSN
1001-8417

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## Abstract The aminothiadiazole (II) on treatment with aromatic aldehydes yielded Schiff bases, which cyclized to thiazolidinone derivatives by reaction with thioglycolic acid. Reaction of II with phenyl isocyanate and phenyl isothiocyanate afforded the carbamide and carbothiamide derivatives, res