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Synthesis and in vitro antimicrobial activity of N-arylquinoline derivatives bearing 2-morpholinoquinoline moiety

✍ Scribed by Jigar A. Makawana; Manish P. Patel; Ranjan G. Patel


Book ID
113523347
Publisher
Chinese Electronic Periodical Services
Year
2012
Tongue
English
Weight
184 KB
Volume
23
Category
Article
ISSN
1001-8417

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Synthesis and in vitro antimicrobial act
✍ Jigar A. Makawana; Manish P. Patel; Ranjan G. Patel πŸ“‚ Article πŸ“… 2011 πŸ› Versita 🌐 English βš– 194 KB

## Abstract A series of new 3-(2-morpholinoquinolin-3-yl)acrylonitrile derivatives (IVa-IVf) has been synthesised by the base-catalysed condensation reaction of 2-morpholinoqionoline-3-carboxaldehydes (IIa-IIc) and 2-cyanomethylbenzimidazoles (IIIa-IIIb). Subsequent regiospecific reduction of the C