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Synthesis and immunoadjuvant activity of 2,2′-O-[2,2′-diacetamido-2,3,2′,3′-tetradeoxy-6,6′-di-O-(2-tetradecyl-hexadecanoyl)-α, α′-trahalose-3,3′-diyl]bis(N-d-lactoyl-l-alanyl-d-isoglutamine)

✍ Scribed by Hideharu Ishida; Yasuyuki Imai; Makoto Kiso; Akira Hasegawa; Takuma Sakurai; Ichiro Azuma

Publisher
Elsevier Science
Year
1989
Tongue
English
Weight
640 KB
Volume
195
Category
Article
ISSN
0008-6215

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✦ Synopsis

The disaccharide of 6-O-(2-tetradecylhexadecanoyl)muramoyl dipeptide coupled through an alpha-(1----1)-alpha linkage, named in the title, and an analog bearing a single peptide moiety, have been synthesized from 2,2'-diazido-2,2'-dideoxy-alpha,alpha'-trehalose. The immunoadjuvant activities of the products were examined.

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