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Synthesis and Herbicidal Activity of α-Hydroxy Phosphonate Derivatives Containing Pyrimidine Moiety

✍ Scribed by Hong Song; Huiyu Mao; Prof. Dr. Deqing Shi


Publisher
John Wiley and Sons
Year
2010
Tongue
English
Weight
77 KB
Volume
28
Category
Article
ISSN
0256-7660

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✦ Synopsis


A series of α-hydroxy phosphonate derivatives containing pyrimidine moiety were designed and synthesized. Their structures were characterized by IR, 1 H NMR, MS and elemental analysis. The results of preliminary herbicidal activities (in vitro) showed that some of the title compounds 2 exhibited moderate herbicidal activities against dicotyledonous weeds (Brassica campestris L), and most of compounds 2 showed better activity against dicotyledonous weeds than monocotyledonous weeds (Echinochloa crus-galli). Further bioassays (in vivo) indicated that some of the title compounds 2 possessed good and selective herbicidal activity against amaranth pigweed (A. retroflexus) in both pre-and post-emergence treatments at the dose of 1.5 kg/ha. For exmple, compounds 2a, 2b and 2e exhibited 100% inhibition against A. retroflexus in pre-emergence treatment, and 91.7%, 98.8% and 99.5% inhibition in post-emergence treatment at the dose of 1.5 kg/ha, respectively.


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