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Synthesis and Glycosidase Inhibitory Activity of Enantiopure Polyhydroxylated Octahydroindoles and Decahydroquinolines, Analogues to Castanospermine.

✍ Scribed by Christine Gravier-Pelletier; William Maton; Gildas Bertho; Yves Le Merrer


Publisher
John Wiley and Sons
Year
2004
Weight
56 KB
Volume
35
Category
Article
ISSN
0931-7597

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Synthesis of Calystegine B2, B3, and B4
✍ M. Isabel García-Moreno; Carmen Ortiz Mellet; José M. García Fernández 📂 Article 📅 2004 🏛 John Wiley and Sons 🌐 English ⚖ 323 KB

## Abstract A practical synthesis of ring‐modified calystegine analogues with a 6‐oxa‐__nor__‐tropane structure has been developed. The methodology relies on the ability of the masked carbonyl group of hexose precursors to act as the electrophilic target for the nitrogen atom of pseudoamide (urea o