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Synthesis and Functionalisation of 2,3-Diheterocycle-Substituted Aziridines

✍ Scribed by Luigino Troisi; Catia Granito; Claudia Carlucci; Fabio Bona; Saverio Florio

Publisher
John Wiley and Sons
Year
2006
Tongue
English
Weight
146 KB
Volume
2006
Category
Article
ISSN
1434-193X

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✦ Synopsis

Abstract

Polyfunctionalyzed aziridines each containing two heterocyclic moieties were prepared by Darzens reactions and the corresponding aziridinyl anions, generated by treatment with strong bases, were investigated. Coupling reaction with electrophiles allowed study of the configurational stability, highlighting the different stabilising effects of the heterocyclic substituents. (© Wiley‐VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2006)

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