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Synthesis and Fluorescence Properties of Dimethylaminonaphthalene—Deoxyuridine Conjugates as Polarity-Sensitive Probes.

✍ Scribed by Akimitsu Okamoto; Kazuki Tainaka; Tomo Unzai; Isao Saito


Publisher
John Wiley and Sons
Year
2007
Weight
11 KB
Volume
38
Category
Article
ISSN
0931-7597

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The chemical synthesis of fluorescent derivatives of atratiyloside (ATR), an inhibitor of the mitochondrial ADP/ATP carrier protein, is described. These derivatives are the following: 6'-O-dansyl ATR, 6'-Odansyl-aminobutyryl ATR, and 6'-O-naphthoyl ATR. The spectral properties of these analogs were