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Synthesis and Evaluation of β-Cyclodextrin-2-Hydroxyethyl Methacrylate Copolymer as a Novel Adsorbent

✍ Scribed by Sreenivasan, K.

Publisher
John Wiley and Sons
Year
1997
Tongue
English
Weight
153 KB
Volume
42
Category
Article
ISSN
0959-8103

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✦ Synopsis

2-Hydroxyethyl methacrylate (0É01 mol) was allowed to react with 0É01 mol of hexamethylene di-isocyanate and the product was coupled to 0É01 mol of b-cyclodextrin to form a new cyclodextrin-based copolymer. The interaction of the polymer with di †erent steroids was investigated and the extent of adsorption was in the order cholesterol [ progesterone [ testosterone. The results indicate that the new polymer matrix could be used for the removal of steroids, particularly cholesterol, from a given medium. The polymer could also be used for sample puriÐcation, such as the removal of progesterone from a mixture prior to its analysis by other analytical techniques. The preliminary results show that the polymer may have interesting clinical and analytical applications.

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