𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Synthesis and evaluation of thioflavin-T analogs as potential imaging agents for amyloid plaques

✍ Scribed by Jung, Soon Jae; Park, Yong Dae; Park, Jeong Hoon; Yang, Seung Dae; Hur, Min Goo; Yu, Kook Hyun

Book ID
120190403
Publisher
Springer-Verlag
Year
2013
Tongue
English
Weight
323 KB
Volume
22
Category
Article
ISSN
1054-2523

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Synthesis and evaluation of two uncharge
Synthesis and evaluation of two uncharged 99mTc-labeled derivatives of thioflavin-T as potential tracer agents for fibrillar brain amyloid
✍ K. Serdons; D. Vanderghinste; M. Van Eeckhoudt; J. Cleynhens; T. de Groot; G. Bo 📂 Article 📅 2009 🏛 John Wiley and Sons 🌐 French ⚖ 264 KB

## Abstract Thioflavin‐T is a fluorescent dye for __in vitro__ detection of fibrillar amyloid β, a protein found in the brain of patients suffering from Alzheimer's disease. We synthesized and biologically evaluated two uncharged ^99m^Tc‐labeled derivatives of thioflavin‐T. The precursors for label

Synthesis and evaluation of two fluorine
Synthesis and evaluation of two fluorine-18 labelled phenylbenzothiazoles as potential in vivo tracers for amyloid plaque imaging
✍ K. Serdons; D. Vanderghinste; M. Van Eeckhoudt; P. Borghgraef; H. Kung; F. Van L 📂 Article 📅 2009 🏛 John Wiley and Sons 🌐 French ⚖ 368 KB

## Abstract Uncharged derivatives of thioflavin‐T have known __in vitro__ and __in vivo__ affinity for amyloid β. We synthesized and evaluated two derivatives with a fluorine‐18 labelled fluoropropoxy substituent either at the 6‐position or at the 2′‐position of the 2‐(4′‐aminophenyl)‐1,3‐benzothia