The synthesis and evaluation of 20 dinitroanilines and related compounds against the obligate intracellular parasite Toxoplasma gondii is reported. Using in vitro cultures of parasites in human fibroblasts, we determined that most of these compounds selectively disrupted Toxoplasma microtubules, and
β¦ LIBER β¦
Synthesis and evaluation of some pyrimidine analogs against toxoplasmosis
β Scribed by M. N. S. Saudi; M. R. Gaafar; M. Z. El-Azzouni; M. A. Ibrahim; M. M. Eissa
- Book ID
- 105770868
- Publisher
- Springer-Verlag
- Year
- 2008
- Tongue
- English
- Weight
- 888 KB
- Volume
- 17
- Category
- Article
- ISSN
- 1054-2523
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