𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Synthesis and evaluation of novel spermidine derivatives as targeted cancer chemotherapeutic agents

✍ Scribed by Stark, Peter A.; Thrall, Brian D.; Meadows, Gary G.; Abdel-Monem, Mahmoud M.


Book ID
126125254
Publisher
American Chemical Society
Year
1992
Tongue
English
Weight
859 KB
Volume
35
Category
Article
ISSN
0022-2623

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## Abstract A novel series of iodinated indomethacin derivatives was synthesized, and evaluated as selective inhibitors of COX‐2. Two candidate compounds __N__‐(__p__‐iodobenzyl)‐2‐(1‐(__p__‐chlorobenzoyl)‐5‐methoxy‐2‐methyl‐1__H__‐indol‐3‐yl)acetamide (3) and 1‐(__p__‐iodobenzyl)‐5‐methoxy‐2‐methy