Synthesis and evaluation of NO-release from symmetrically substituted furoxans
β Scribed by William F. Nirode; Jessica M. Luis; Jordan F. Wicker; Nanette M. Wachter
- Book ID
- 108073931
- Publisher
- Elsevier Science
- Year
- 2006
- Tongue
- English
- Weight
- 103 KB
- Volume
- 16
- Category
- Article
- ISSN
- 0960-894X
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A series of novel furoxan-based nitric oxide (NO)-releasing derivatives of glycyrrhetinic acid (GA) were designed, synthesized, and evaluated for their in vitro cytotoxicity against human hepatocellular carcinoma (HCC) and non-tumor liver cells. Five furoxan/GA hybrids, 7b-d, 7f, and 7g, displayed p
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