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Synthesis and evaluation of isoleucine derived angiotensin II AT2 receptor ligands

✍ Scribed by Veron, Jean-Baptiste; Joshi, Advait; Wallinder, Charlotta; Larhed, Mats; Odell, Luke R.

Book ID
121421394
Publisher
Elsevier Science
Year
2014
Tongue
English
Weight
377 KB
Volume
24
Category
Article
ISSN
0960-894X

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## Abstract Three ^11^C‐radiolabelled high‐affinity nonpeptide AT~2~ receptor‐selective ligands were synthesized and one of these was evaluated as positron emission tomography (PET) tracer. The labelling reaction was performed via palladium(0)‐mediated aminocarbonylation of the aryl iodide substrat