✦ LIBER ✦

Synthesis and evaluation of diacylhydrazines as inhibitors of the interleukin-1β converting enzyme (ICE)

✍ Scribed by Todd L. Graybill; Roland E. Dolle; Carla T. Helaszek; Mark A. Ator; Joost Strasters

Publisher: Elsevier Science
Year: 1995
Tongue: English
Weight: 374 KB
Volume: 5
Category: Article
ISSN: 0960-894X
DOI: 10.1016/0960-894x(95)00194-x

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Synthesis and Evaluation of Thiazepines

Synthesis and Evaluation of Thiazepines as Interleukin-1β Converting Enzyme (ICE) Inhibitors.

✍ Christopher D. Ellis; et al. et al. 📂 Article 📅 2006 🏛 John Wiley and Sons ⚖ 14 KB

ChemInform Abstract: Pyridone-Based Pept

ChemInform Abstract: Pyridone-Based Peptidomimetic Inhibitors of Interleukin-1β- converting Enzyme (ICE).

✍ G. SEMPLE; D. M. ASHWORTH; G. R. BAKER; A. R. BATT; A. J. BAXTER; D. W. M. BENZI 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 30 KB 👁 1 views

Synthesis and Evaluation of Novel 8,6-Fu

Synthesis and Evaluation of Novel 8,6-Fused Bicyclic Peptidomimetic Compounds as Interleukin-1β Converting Enzyme Inhibitors.

✍ Steven V. O'Neil; et al. et al. 📂 Article 📅 2006 🏛 John Wiley and Sons ⚖ 26 KB 👁 1 views

ChemInform Abstract: Structure-Based Des

ChemInform Abstract: Structure-Based Design of Nonpeptide Inhibitors of Interleukin-1β Converting Enzyme (ICE, Caspase-1).

✍ Aurash B. Shahripour; et al. et al. 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 34 KB 👁 1 views

## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable v

ChemInform Abstract: Peptide Based Inter

ChemInform Abstract: Peptide Based Interleukin-1β Converting Enzyme (ICE) Inhibitors: Synthesis, Structure Activity Relationships and Crystallographic Study of the ICE-Inhibitor Complex.

✍ Yoshinori Okamoto; et al. et al. 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 32 KB 👁 1 views

α-((Tetronoyl)oxy)- and α-((tetramoyl)ox

α-((Tetronoyl)oxy)- and α-((tetramoyl)oxy)methyl ketone inhibitors of the interleukin-1β converting enzyme (ICE)

✍ Todd L. Graybill; Catherine P. Prouty; Gary J. Speier; Denton Hoyer; Roland E. D 📂 Article 📅 1997 🏛 Elsevier Science 🌐 English ⚖ 386 KB

Aryl-substituted tetronic acids, tetramic acids, and cyclic ~-dicarbonyl moieties were evaluated as leaving groups in the peptidyl-COCH2-X type inhibitor iii. Tripeptidyl aspartyl et-((tetronoyl)oxy)-and ~-((tetramoyl)oxy)methyl ketone derivatives demonstrate potent time-dependent inhibition (kob,/[