Synthesis and evaluation of chitosan-vitamin C complexes

✍ Scribed by Tian Xiaolin; Tian Dafeng; Wang Zhongyan; Mo Fengkui

• Publisher: John Wiley and Sons
• Year: 2009
• Tongue: English
• Weight: 231 KB
• Volume: 114
• Category: Article
• ISSN: 0021-8995
• DOI: 10.1002/app.30918

✦ Synopsis

Abstract

Chitosan (CS) is a biocompatible, biodegradable, and nontoxic polysaccharide polymer. It dissolves in water only if the pH is lower than 6.5. To extend its range of application, many water‐soluble derivatives have, therefore, been prepared. In this research, chitosan‐vitamin C complexes (CSVC) were synthesized and characterized with FTIR, DSC, and ^1^H‐NMR. The solubility of CSVC in distilled water was greatly improved. The •O~2~^‐^ scavenging activity of CSVC was compared with CS and vitamin C (VC) by measuring the auto‐oxidation rate of pyrogallic acid. Results showed that the scavenging activity on •O~2~^−^ by CSVC was stronger than that by CS. © 2009 Wiley Periodicals, Inc. J Appl Polym Sci, 2009