Synthesis and evaluation of antibacterial activity of new derivatives of pyrimido[4,5-e][1,3,4]oxadiazine
β Scribed by Bakavoli, Mehdi (author);Rahimizadeh, Mohammad (author);Shiri, Ali (author);Eshghi, Hossein (author);Simin Vaziri-Mehr (author);Pordeli, Parvaneh (author);Nikpour, Mohsen (author)
- Book ID
- 121402238
- Publisher
- Walter de Gruyter GmbH & Co. KG
- Year
- 2011
- Tongue
- English
- Weight
- 167 KB
- Volume
- 17
- Category
- Article
- ISSN
- 0793-0283
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## Abstract Several derivatives of the new pyridazino[4,3βe][1,3,4]oxadiazine ring system were prepared, and their antibacterial evaluations were performed on four different Gramβnegative and Gramβpositive bacteria. J. Heterocyclic Chem., (2010).
## Abstract The compound (IXd) is tested on the cancer cell lines MCFβ7 and HepG2 and decreases viability of the cells in a concentrationβdependent manner.
## Abstract Starting from pyrimido[4,5βe][1,3,4]oxadiazines **(****3a**, **3b**, **3c****)**, a synthetic pathway to [1,2,4]triazolo[4β²,3β²:1,2]pyrimido[4,5βe][1,3,4]oxadiazines **(****5a**, **5b**, **5c**, **5d**, **5e**, **5f**, **5g**, **5h**, **5i****)** is described. The reaction of pyrimido[4,