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Synthesis and Evaluation of an Enantiomerically Enriched Bifunctional Chelator for 64 Cu-Based Positron Emission Tomography (PET) Imaging

✍ Scribed by Chong, Hyun-Soon; Sun, Xiang; Zhong, Yongliang; Bober, Kamil; Lewis, Michael R.; Liu, Dijie; Ruthengael, Varyanna C.; Sin, Inseok; Kang, Chi Soo


Book ID
121785160
Publisher
John Wiley and Sons
Year
2014
Tongue
English
Weight
584 KB
Volume
2014
Category
Article
ISSN
1434-193X

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The novel 2-mercaptoimidazole derivatives, 1-[4-((2-methoxyphenyl)-1-piperazinyl)butyl]-2-mercaptoimidazole (3) and methyl[4-((2-methoxyphenyl)-1-piperazinyl))butyl] (2-mercapto-1-methylimidazol-5-yl)methanamide ( 8), were efficiently labelled with 11 C through methylation of the thioketone function