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Synthesis and Evaluation of a Novel Series of Pyrrolizine Derivatives as Dual Cyclooxygenase-1 and 5-Lipoxygenase Inhibitors

✍ Scribed by Stefan Laufer; Hans-Günter Striegel; Karola Neher; Pia Zechmeister; Cornelia Donat; Katrin Stolingwa; Sibylle Baur; Susanne Tries; Thomas Kammermeier; Gerd Dannhardt; Werner Kiefer


Publisher
John Wiley and Sons
Year
1997
Tongue
English
Weight
625 KB
Volume
330
Category
Article
ISSN
0365-6233

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Hydroxylamine analogs of 2,6 di-t-butylp
✍ James B. Kramer; Thomas Capiris; Jagadish C. Sircar; David T. Connor; Dirk A. Bo 📂 Article 📅 1995 🏛 Elsevier Science 🌐 English ⚖ 690 KB

The preparation of hydroxylamine analogs of 2,6-di-tert-butylphenols (DTBP) and the inhibition of cyclooxygenase (CO) and 5-lipoxygenase (5-LO) by these compounds is discussed.