Synthesis and Evaluation of 5-Aryl-3-(4-hydroxyphenyl)-1,3,4-oxadiazole-2-(3H)-thiones as P-Glycoprotein Inhibitors.
β Scribed by Chatchanok Loetchutinat; Francois Chau; Samlee Mankhetkorn
- Publisher
- John Wiley and Sons
- Year
- 2003
- Weight
- 75 KB
- Volume
- 34
- Category
- Article
- ISSN
- 0931-7597
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The fragmentation behaviour of 3,4-disubstituted 1,2,4-oxadiazole-5(4H)-thiones under electron impact (EI) can be explained by postulating a predominant rearrangement to the corresponding 3,4-disubstituted 1,2,4-thiadiazole-5(4H)-ones before further fragmentation. This postulate is confirmed by a co