β Scribed by Sang J. Chung; Dong H. Kim
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A series of novel 7- (3-aminopyrrolo[3,4-c]pyrazol-5(2H,4H,6H)-yl)-6-fluoro-4-oxo-1,4-dihydroquinoline-3carboxylic acid derivatives was designed, synthesized and characterized by 1 H-NMR, MS and HRMS. These fluoroquinolones were evaluated for their in-vitro antibacterial activity against representat
Synthesis, Pharmacokinetics, and Biological Activity of a Series of New Pyridonecarboxylic Acid Antibacterial Agents Bearing a 5-Fluoro-2-pyridyl Group or a 3-Fluoro-4-pyridyl Group at N-1. -A variety of new quinolones bearing fluorinated pyridyl groups at N1 ( cf. (VIII), (IX); 18 examples) are syn
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