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Synthesis and evaluation of [18F]fluororasagiline, a novel positron emission tomography (PET) radioligand for monoamine oxidase B (MAO-B)

✍ Scribed by S. Nag; L. Lehmann; G. Kettschau; T. Heinrich; A. Thiele; A. Varrone; B. Gulyas; C. Halldin


Book ID
113495752
Publisher
Elsevier Science
Year
2012
Tongue
English
Weight
711 KB
Volume
20
Category
Article
ISSN
0968-0896

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Eight normal subjects (3 females and 5 males) were studied using intravenous L-[11C] deprenyl and positron emission tomography. In a single blind study one subject received tracer alone, one subject received an oral pre-dose of 20 mg of L-deprenyl and 6 subjects received oral pre-doses of 10 to 50 m