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Synthesis and degradation of hepatic metallothionein in mice differing in susceptibility to cadmium mortality

โœ Scribed by J. E. Piletz; R. D. Andersen; W. Berry; H. R. Herschman

Book ID
104783968
Publisher
Springer
Year
1983
Tongue
English
Weight
920 KB
Volume
21
Category
Article
ISSN
0006-2928

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Exposure to different forms of cadmium in mice: Differences in metallothionein and alphafetoprotein mRNA induction in liver and kidney
โœ Koropatnick, James ;Cherian, M. George ๐Ÿ“‚ Article ๐Ÿ“… 1988 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 716 KB

Cadmium (Cd) exposure in mice induces transcription of metallothionein (MT) mRNA and protein accumulation in both liver and kidney. Resistance to hepatotoxicity through chronic exposure to heavy metals is the result of this induction. However, the same chronic exposure results in damage to kidney. W