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Synthesis and cytotoxicity of some biurets against human breast cancer T47D cell line

✍ Scribed by Shamileh Fouladdel; Ali Khalaj; Neda Adibpour; Ebrahim Azizi

Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
488 KB
Volume
20
Category
Article
ISSN
0960-894X

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✦ Synopsis

Design, synthesis and cytotoxicity of several known and novel biurets against human breast cancer T47D cell line in comparison to doxorubicin are described. Biurets incorporating 2-methyl quinoline-4-yl and benzo[d]thiazol-2-ylthio moieties showed higher cytotoxicity and decreased cell viability in a concentration-and time-dependent manner.

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