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Synthesis and cytotoxic activity of phenyl-hexahydropyrrolo[3,4-c]carbazoles

✍ Scribed by Esther Caballero; Francine García; Dolores Grávalos; Manuel Medarde; Heidi Sahagún; Fernando Tomé

Book ID
103983580
Publisher
Elsevier Science
Year
1996
Tongue
English
Weight
270 KB
Volume
6
Category
Article
ISSN
0960-894X

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✍ Sylvain Routier; Gérard Coudert; Jean-Yves Mérour 📂 Article 📅 2001 🏛 Elsevier Science 🌐 French ⚖ 157 KB

New naphthocarbazoles 1 were built from protected 3-(3-indolyl)-4-bromo-N-methylmaleimide in four steps using palladium-catalysed cross-coupling reactions such as Suzuki reaction of 3-methoxy-2-boronic acid and Heck cyclisation of triflate.