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Synthesis and Cytotoxic Activity of Halogen-Containing Dinitromethyl-1,3,5-triazine Derivatives

✍ Scribed by A. A. Gidaspov; V. V. Bakharev; E. V. Kachanovskaya; E. A. Kosareva; M. V. Galkina; E. V. Ekimova; N. G. Yakunina; Yu. N. Bulychev

Book ID: 111603420
Publisher: Springer
Year: 2004
Tongue: English
Weight: 125 KB
Volume: 38
Category: Article
ISSN: 0091-150X
DOI: 10.1023/b:phac.0000048901.45151.7f

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## Abstract Reaction of 6‐phenyl‐4‐thioxo‐1,3,5‐triazine‐2‐one with alkyl halide in the presence of 1 equiv. of sodium hydroxide resulted in 4‐alkylthio‐6‐phenyl‐1,3,5‐triazine‐2‐one in good yield, whereas the above reaction provided 2‐alkoxyl‐4‐alkylthio‐6‐phenyl‐1,3,5‐triazine in the presence of