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Synthesis and Cytotoxic Activities of a New Benzo[ c ]phenanthridine Alkaloid, 7-Hydroxynitidine, and Some 9-Oxygenated Benzo[ c ]phenanthridine Derivatives

โœ Scribed by Nakanishi, Takeshi; Suzuki, Masanobu


Book ID
121337709
Publisher
American Chemical Society
Year
1999
Tongue
English
Weight
60 KB
Volume
1
Category
Article
ISSN
1523-7060

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Antileukemic benzotclphenanthridine alkaloids, fagaronine (l(Y) and nitidine (1~) were synthesized from the corresponding protoberberines through C6-N bond fission and subsequent cyclization between C6 and Cl3 position of the protoberberines. Fully aromatized 2,3,8,9\_tetraoxygenated benzo[clphenant