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Synthesis and conformational analysis of phosphorus-derivatized no-base analogues of 3′, 5′ -cyclic nucleotides

✍ Scribed by Rob J. M. Hermans; Henk M. Buck


Book ID
104588882
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
550 KB
Volume
107
Category
Article
ISSN
0165-0513

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Conformational analysis of a cyclic nucl
✍ Jean Noël Lespinasse; Dane Vasilescu 📂 Article 📅 1974 🏛 Wiley (John Wiley & Sons) 🌐 English ⚖ 573 KB

## Abstract The extended Hückel theory (EHT) was used as a quantum mechanical approach for the determination of the best conformation of cyclic AMP. Both geometrical and quantum mechanical studies were necessary to ascertain the configuration of the sugar ring and phosphate ring. This was due to th