Synthesis and Conformational Analysis of Macrocyclic Dihydroxystilbenes Linked between the para–para Positions
✍ Scribed by Carmen Mateo; Vilmarí López; Manuel Medarde; Rafael Peláez
- Publisher
- John Wiley and Sons
- Year
- 2007
- Tongue
- English
- Weight
- 403 KB
- Volume
- 13
- Category
- Article
- ISSN
- 0947-6539
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## Abstract A small number of macrocyclic dilactones of type **3**, __i.e.__, **9, 10, 11**, and epi‐**11**, comprising a 3,4‐dihydroxypentanoic acid unit, the pharmacophore of aplysiatoxin, and a conformationally preorganized __ω__‐hydroxynonanoic acid unit were synthesized. Conformational analysi
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