A mono-proline analogue of the potent anthelmintic cyclooctadepsipeptide PF1022A has been synthesized. NMR studies in combination with molecular dynamics simulations demonstrate that the conürmation of this analogue is both rigidiüed and distorted compared with the asymmetric conformation of PF1022A
✦ LIBER ✦
Synthesis and Conformation Studies of a Dodecaazanonacyclotetratetracontane
✍ Scribed by M. Rachel Suissa; Christian Rømming; Johannes Dale
- Publisher
- John Wiley and Sons
- Year
- 1999
- Tongue
- English
- Weight
- 314 KB
- Volume
- 5
- Category
- Article
- ISSN
- 0947-6539
No coin nor oath required. For personal study only.
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