Synthesis and Chiroptical Properties of a New Type of Chiral Depsipeptide Dendrons.
β Scribed by Boris Buschhaus; Walter Bauer; Andreas Hirsch
- Publisher
- John Wiley and Sons
- Year
- 2003
- Weight
- 67 KB
- Volume
- 34
- Category
- Article
- ISSN
- 0931-7597
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By use of an asymmetric Ullmann coupling involving chiral naphthalene oxazolines 1, the title compounds were prepared in good yields and with high diastereoselectivity. Hydrolysis of the binaphthyl oxazolines 2 led to the di-aldehydes 5, which were transformed into the azepine derivative, 6. The lat