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Synthesis and characterization of tetramethylrhodaminethiocarbamoyl-(Glu1)–epidermal mitosis-inhibiting pentapeptide

✍ Scribed by M Bramucci; A Miano; L Quassinti; O Murri; D Amici


Book ID
117348699
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
151 KB
Volume
102
Category
Article
ISSN
0167-0115

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## Abstract The antivirally active 3′‐deoxyadenylyl‐(2′–5′)‐3′‐deoxyadenylyl‐(2′–5′)‐3′‐deoxyadenosine (cordycepin trimer core) was modified at the 2′‐ or 5′‐terminus, by attachment of cholesterol __via__ a carbonate bond (→ 15) or a succinate linker (→ 16 and 27) to improve cell permeability. The