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Synthesis and characterization of some heterocyclic derivatives by cyclization of carbohydrate thiosemicarbazone — part II

✍ Scribed by M. A. Martins Alho; N. B. D'Accorso


Publisher
Journal of Heterocyclic Chemistry
Year
2000
Tongue
English
Weight
254 KB
Volume
37
Category
Article
ISSN
0022-152X

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✦ Synopsis


Abstract

The syntheses of 2,3‐dihydro‐1,3,4‐thiadiazoles and 1,3,4‐thiadiazoles from 1,2‐O‐isopropylidene‐α‐D‐xylo‐1,5‐pentadialdo‐1,4‐furanose thiosemicarbazone are described. The new compounds as well as the intermediate products are physically and spectroscopically characterized. We discuss a possible mechanistic pathway for heterocyclization in this particular substrate, using computational calculation.


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