Synthesis and characterization of several cephalothin derivatives modified with germanium-containing moieties

✍ Scribed by Yoshito Takeuchi; Yumiko Kase; Yoko Imafuku

• Publisher: John Wiley and Sons
• Year: 2005
• Tongue: English
• Weight: 118 KB
• Volume: 19
• Category: Article
• ISSN: 0268-2605
• DOI: 10.1002/aoc.806

✦ Synopsis

Abstract

A cepham, cephalothin (4), was modified with germanium‐containing moieties. Their structures were confirmed chiefly based on electrospray ionization mass spectrometry and NMR spectroscopy and their antibacterial properties were tested. None of these exhibited activity strong enough to be used as a medicine. Copyright © 2005 John Wiley & Sons, Ltd.