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Synthesis and characterization of photoactivatable peptide agonists of the human thrombin receptor

✍ Scribed by Rainer Bischoff; Yves Cordier; Ulla B. Rasmussen; Yasmin Schlesinger; Christian Gachet; Michel Jaquinod; Brian Tripet; Pele C.S. Chong; Andrea Pavirani


Book ID
115927203
Publisher
Elsevier Science
Year
1994
Tongue
English
Weight
634 KB
Volume
349
Category
Article
ISSN
0014-5793

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Modified thrombin receptor-agonist pepti
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Analogs 2-24 of the N-terminal tripeptide region of the tethered peptide ligand for human thrombin receptor have been synthesized for elucidation of the receptor bound conformation of the ligand peptide and the conformational analysis of model structures 25-30 of those peptide analogs suggested a pl