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Synthesis and characterization of oligodeoxynucleotides containing O6-methyl-, O6-ethyl-, and O6-isopropylguanine

✍ Scribed by Li, Benjamin F. L.; Swann, Peter F.

Book ID
126924156
Publisher
American Chemical Society
Year
1989
Tongue
English
Weight
897 KB
Volume
28
Category
Article
ISSN
0006-2960

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Solid-phase synthesis of oligodeoxynucle
Solid-phase synthesis of oligodeoxynucleotides containing 6-O-alkylguanosines
✍ H. C. P. F. Roelen; H. F. Brugghe; H. van den Elst; J. C. Klein; G. A. van der M 📂 Article 📅 2010 🏛 Elsevier Science 🌐 English ⚖ 929 KB

## Abstract High‐quality oligodeoxynucleotides having an 6‐__O__‐alkyl‐2′‐deoxyguanosine (alkyl = methyl, ethyl, __n__‐propyl or __n__‐hexyl) residue at a predetermined position can be obtained via a solid‐phase approach using the respective 2‐cyanoethyl __N,N__‐diisopropylphosphoramidites of 5′‐__