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Synthesis and characterization of N-(2-hydroxy)propyl-3-trimethyl ammonium chitosan chloride for potential application in gene delivery

โœ Scribed by Bo Xiao; Ying Wan; Xiaoyu Wang; Qichen Zha; Haoming Liu; Zhiye Qiu; Shengmin Zhang


Book ID
113550494
Publisher
Elsevier Science
Year
2012
Tongue
English
Weight
945 KB
Volume
91
Category
Article
ISSN
0927-7765

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N-(2-Hydroxy) propyl-3-trimethylammonium chitosan chloride (HTCC) was synthesized by the reaction of glycidyltrimethylammonium chloride (GTMAC) and chitosan. The reaction product was a water-soluble chitosan derivative, and showed excellent antimicrobial activity. HTCC was blended with polyacryloni