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Synthesis and Characterization of Enzymatically Biodegradable PEG and Peptide-Based Hydrogels Prepared by Click Chemistry

โœ Scribed by van Dijk, Maarten; van Nostrum, Cornelus F.; Hennink, Wim E.; Rijkers, Dirk T. S.; Liskamp, Rob M. J.


Book ID
126061911
Publisher
American Chemical Society
Year
2010
Tongue
English
Weight
643 KB
Volume
11
Category
Article
ISSN
1525-7797

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## Abstract Biodegradable hydrogels were synthesized by the click reaction of 4โ€arm azidoโ€terminated PEG differing in molecular weight (2โ€‰100 and 8โ€‰800) and two alkyneโ€terminated peptides: [alkyne]โ€GFLGKโ€[alkyne] and ([alkyne]โ€GFLG)~2~K. The physical properties of in situ formed hydrogels were exam